Catheter-based Renal Sympathetic Denervation May Not Be Appropriate for the Treatment of Hypertension Caused by Primary Aldosteronism: a Case Report

Previous studies on the treatment of hypertension with RDN were all aimed at patients with essential hypertension, while there were few studies on secondary hypertension, especially primary aldosteronism. Whether RDN can be used to treat hypertension due to primary aldosteronism remains a subject of much debate. Here, we present a 54-year-old man with a history of resistant hypertension spanning more than 10 years; secondary hypertension was ruled out 6 years ago, and he underwent renal sympathetic denervation (RDN) in 2016. The patient’s blood pressure had been controllable after half a year of RDN. After six months, the patient’s blood pressure began to rise gradually and he began to increase the type of antihypertensive medication. The patient was diagnosed with aldosteronoma 1 year ago and underwent laparoscopic adrenalectomy. After that, the patient’s blood pressure controlled well.